Expedition 49 was the 49th expedition to the International Space Station.
Anatoli Ivanishin, Kathleen Rubins and Takuya Onishi transferred from Expedition 48. Expedition 49 began upon the departure of Soyuz TMA-20M on September 6, 2016 and concluded upon the departure of Soyuz MS-01 in October 2016. The crew of Soyuz MS-02 then transferred to Expedition 50.
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