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The sixth cholera pandemic (1899–1923) was a major outbreak of cholera beginning in India, where it killed more than 800,000 people, and spreading to West Asia, North Africa, Eastern Europe, and Russia.

The outbreak of the pandemic is thought to have started at the Haridwar Kumbh Mela. The epidemic spread to Europe via Punjab, Afghanistan, Persia, and southern Russia. An outbreak of cholera in New York City from 1910 to 1911 is thought to be part of the pandemic, having spread through infected people aboard the steamship Moltke which was transporting passengers from Naples. In 1913, there was a cholera outbreak in forces of the Romanian Army which were taking part in military operations of the Second Balkan War in Bulgarian areas.