Bầu cử tổng thống Hoa Kỳ tại Mississippi năm 2016

The 2016 United States presidential election in Mississippi was held on Tuesday, November 8, 2016, as part of the 2016 United States presidential election in which all 50 states plus the District of Columbia participated. Mississippi voters chose electors to represent them in the Electoral College via a popular vote, pitting the Republican nominee, businessman Donald Trump, and running mate Indiana Governor Mike Pence against Democratic nominee, former Secretary of State Hillary Clinton, and her running mate Virginia Senator Tim Kaine. Mississippi has six electoral votes in the Electoral College.

Mississippi has not voted Democratic since 1976. Since that time, Republicans have dominated the state's political elections, and so Trump was widely expected to win the state. Indeed, Trump carried it with 57.94% of the vote, while Clinton received 40.11%. Trump's 17.83% margin of victory was a 6.33% increase over the 11.50% margin of victory by which Republican nominee Mitt Romney won the state over Barack Obama in 2012. This also marked the first time since 1988 that Madison County voted more Democratic than the state as a whole. Trump became the first Republican to win the White House without carrying Oktibbeha County since Richard Nixon in 1968, as well as the first to do so without carrying Copiah, Pike, or Yazoo Counties since Ronald Reagan in 1980.