Bầu cử Thượng viện Hoa Kỳ tại Pennsylvania năm 2012

The 2012 United States Senate election in Pennsylvania was held on November 6, 2012, alongside a presidential election, other elections to the United States Senate in other states, elections to the United States House of Representatives, and various state and local elections. Incumbent Democratic U.S. Senator Bob Casey, Jr. ran for and won re-election to a second term, defeating Republican nominee Tom Smith, and Libertarian nominee Rayburn Smith.

The requisite primary elections occurred on April 24, 2012, during which the Republicans and Democrats selected nominees for the general election. The Republican primary was a five-way contest. Tom Smith, the eventual nominee, faced David A. Christian, Sam Rohrer, Marc Scaringi, and Steve Welch. The Democratic primary was not heavily contested. Incumbent Bob Casey, Jr., defeated Joseph Vodvarka by a wide margin. The Libertarian Party nominated Rayburn Smith.

Casey led most pre-election polls and eventually defeated his opponents to win re-election to a second term in the U.S. Senate. The election was the first time a Democrat won re-election to the U.S. Senate from Pennsylvania since the 1962 election. As of 2026, this is the last time that Fayette County and Luzerne County voted Democratic in a Senate election. This is also the only time since 1956 that Democrats have won a Pennsylvania U.S. Senate race in a presidential year.