Expedition 50

Expedition 50 was the 50th expedition to the International Space Station. Shane Kimbrough, Andrey Borisenko and Sergey Ryzhikov transferred from Expedition 49. Expedition 50 began upon the departure of Soyuz MS-01 on October 28, 2016 and was concluded upon the departure of Soyuz MS-02 on April 10, 2017. The crew of Soyuz MS-03 were transferred to Expedition 51.

After the launch of Soyuz MS-03, Peggy Whitson, at age 56, became the oldest woman to fly into space. By taking command of Expedition 51 on April 10, 2017, she also became the first woman to command two ISS expeditions (after Expedition 16 in 2007–2008). Soyuz MS-03 docked at the International Space Station on November 19, 2016, bringing the total number of people in the station to 6.