Bầu cử tổng thống Hoa Kỳ tại Mississippi năm 1840

A presidential election was held in Mississippi from November 3–4, 1840 as part of the 1840 United States presidential election. Voters chose four representatives, or electors to the Electoral College, who voted for President and Vice President.

Mississippi voted for the Whig candidate, William Henry Harrison, over Democratic candidate Martin Van Buren. Harrison won Mississippi by a margin of 6.86%. As of 2024, this is the only presidential election in American history in which Mississippi has voted for a different candidate than Alabama. This would also be the last time a Democrat (or Democratic splinter) candidate lost Mississippi until 1872.