The Great Ryōgoku Fire, or Great Kanda Fire, occurred on 26 January 1881, in Tokyo, Japan. The fire was the largest and most destructive of the Meiji era.
At about 2 a.m., two fires broke out simultaneously on the path along the Kanda River. Due to strong seasonal winds, the fire spread and was carried throughout Tokyo by the Ryōgoku Bridge. The fire destroyed 15,221 homes across over 100 acres, including much of the Edo period architecture. Over 36,000 people were left homeless.
On 11 February 1881, another major fire broke out in Hisamatsuchō.
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Text from the Wikipedia article “Great Fire of Kanda”, available under CC BY-SA 4.0.