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Rebellion
1526 Espadán rebellion
- March 1526
- Serra d'Espadà
- Europe
Meanwhile, elsewhere
- 1517 – 1648Protestant Reformation
- 1519 – 1521Spanish conquest of the Aztec EmpireMesoamerica and the Caribbean
- 1532 – 1572Spanish conquest of the Inca EmpireSouth America
- 1493 – 1898Spanish colonization of the Americas
- 1530Augsburg Confession
- 23 August 1514Battle of ChaldiranMiddle East
- 1543Copernican heliocentrism
- 1487 – 1583Muscovite-Lithuanian Wars